Louisa Hades is a strict school teacher. She is also the school villain. She basically became so strict that she eventually entered goddess-hood. Because of this, each time she gets angry, not only does she grow stronger and eviler but she also gains considerable height, but in her human form, she was rather short.
Louisa appears in All Star Smashers as a Primary Spirit, as a legend class, where you must fight Hilary at the Final Destination to obtain her. When fighting Hilary, Toby Grady can be the only Assist Trophy summoned. Hilary will also be much taller and lighter, and after 10 seconds, a sudden death screen occurs, but the enemy's damage remains the same.